DRUG INTERACTIONS WITH DIAZEPAM
نویسندگان
چکیده
منابع مشابه
Drug Interactions with Diazepam
Diazepam is a benzodiazepine derivative with anxyolitic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, antitremor, and amnestic activity. It is metabolized in the liver by the cytochrome P (CYP) 450 enzyme system. Diazepam is N-demethylated by CYP3A4 and CYP2C19 to the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 to the active metabolite temazepam. N-desm...
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ژورنال
عنوان ژورنال: Acta medica medianae
سال: 2011
ISSN: 0365-4478
DOI: 10.5633/amm.2011.0214